Is Indianapolis safer than Durham?
No. Durham's crime index is 193 versus 216 in Indianapolis, and its violent crime index is 163 versus 246, using 2024-2025 FBI data.
Indianapolis is cheaper. Median rent is $1,156 a month versus $1,508 in Durham.
The cost gap between Indianapolis and Durham is the real story here. Indianapolis comes in 23% cheaper on typical rent ($1,156 vs $1,508), which over a year adds up to $4,224. Median household income runs $66,219 in Indianapolis and $81,619 in Durham.
Durham is not a close call here. It leads on the job market, safety, and weather by margins that add up in daily life. Indianapolis makes sense if you have a specific reason, a job offer, family, or a neighborhood you already know, but on the numbers alone Durham is the stronger move.
The rent gap is real but neighborhoods matter. Indianapolis at $1,156 average has pockets that run $956 and others at $1,556: your actual number depends on which part of the city you land in.