Is Louisville safer than Port St Lucie?
No. Port St Lucie's crime index is 38 versus 209 in Louisville, and its violent crime index is 37 versus 207, using 2024-2025 FBI data.
Louisville is cheaper. Median rent is $1,120 a month versus $1,937 in Port St Lucie.
Safety is where Louisville and Port St Lucie split most clearly. Port St Lucie scores 171 points better on the crime index, a gap that shows up in evening walks, parking situations, and insurance rates. Rent runs $1,120 in Louisville and $1,937 in Port St Lucie.
Port St Lucie is not a close call here. It leads on the job market, safety, and weather by margins that add up in daily life. Louisville makes sense if you have a specific reason, a job offer, family, or a neighborhood you already know, but on the numbers alone Port St Lucie is the stronger move.
The rent gap is real but neighborhoods matter. Louisville at $1,120 average has pockets that run $920 and others at $1,520: your actual number depends on which part of the city you land in.