Is San Diego safer than Buffalo?
Yes. San Diego's crime index is 106 versus 221 in Buffalo, and its violent crime index is 114 versus 216, using 2024-2025 FBI data.
Buffalo is cheaper. Median rent is $1,046 a month versus $2,313 in San Diego.
The income gap between San Diego and Buffalo is significant: $108,077 median household versus $50,041. That spread matters more if you are job hunting locally than if you are remote. Typical rent is $2,313 in San Diego and $1,046 in Buffalo.
San Diego is not a close call here. It leads on the job market, safety, and weather by margins that add up in daily life. Buffalo makes sense if you have a specific reason, a job offer, family, or a neighborhood you already know, but on the numbers alone San Diego is the stronger move.
The rent gap is real but neighborhoods matter. Buffalo at $1,046 average has pockets that run $846 and others at $1,446: your actual number depends on which part of the city you land in.