Is Mesa safer than Port St Lucie?
No. Port St Lucie's crime index is 38 versus 108 in Mesa, and its violent crime index is 37 versus 131, using 2024-2025 FBI data.
Mesa is cheaper. Median rent is $1,620 a month versus $1,937 in Port St Lucie.
Safety is where Mesa and Port St Lucie split most clearly. Port St Lucie scores 70 points better on the crime index, a gap that shows up in evening walks, parking situations, and insurance rates. Rent runs $1,620 in Mesa and $1,937 in Port St Lucie.
This is a genuine split. Mesa wins on cost of living and the job market and Port St Lucie wins on safety. Which matters more depends entirely on how you live: remote workers and families weight these categories differently than commuters or single professionals.
The rent gap is real but neighborhoods matter. Mesa at $1,620 average has pockets that run $1,420 and others at $2,020: your actual number depends on which part of the city you land in.