Rent
Neck and neck
San Diego and Cape Coral are about even on rent.
San Diego
$2,150/mo
Cape Coral
$2,150/mo
What this means for your life
Typical rent in San Diego is $2,150 a month versus $2,150 in Cape Coral, close enough that housing cost should not decide the move by itself. Factor it into your budget alongside salary differences between the two markets, then pick the city that wins the categories you actually live in: safety, schools, pay, or weather.