Is San Diego safer than Port St Lucie?
No. Port St Lucie's crime index is 38 versus 106 in San Diego, and its violent crime index is 37 versus 114, using 2024-2025 FBI data.
Port St Lucie is cheaper. Median rent is $1,937 a month versus $2,313 in San Diego.
Safety is where San Diego and Port St Lucie split most clearly. Port St Lucie scores 68 points better on the crime index, a gap that shows up in evening walks, parking situations, and insurance rates. Rent runs $2,313 in San Diego and $1,937 in Port St Lucie.
Neither city has a clear overall edge here. Port St Lucie costs less and San Diego pays more: the right call depends on whether you are optimizing for take-home pay or monthly burn rate. Both are defensible choices for different reasons.
The rent gap is real but neighborhoods matter. Port St Lucie at $1,937 average has pockets that run $1,737 and others at $2,337: your actual number depends on which part of the city you land in.